http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9403757-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1224e3c07b7cc5684ee81d9e1e5ee15c |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0438 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C235-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C237-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-14 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-46 |
filingDate | 2013-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53c79428cb8c2cf8506b5e8eb6985ff9 |
publicationDate | 2016-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-9403757-B2 |
titleOfInvention | Preparation of intermediates of X-ray contrast agents |
abstract | The present invention relates to a process for the preparation of iodinated X-ray contrast agents and in particular to key intermediates thereof. It particularly relates to an improved process for preparation of 5-acetamido-N,N′-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide (Compound A) or N,N′-bis(2,3-dihydroxypropyl)-5-formamido-2,4,6-triiodoisophthalamide (Compound C), which are intermediates in the industrial preparation of non-ionic X-ray contrast agents. More particularly the invention provides a process for deacylation of the acylated hydroxyl groups of an intermediate compound of Compound A and Compound C. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11059021-B2 |
priorityDate | 2012-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 112.