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filingDate 2013-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e90b9a09d741d0573da0b754a98d87c
publicationDate 2016-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-9365813-B2
titleOfInvention Bioreactor system and methods for alternative cell culture between static and dynamic
abstract The invention relates to a bioreactor system characterized by its capacity in cultivating cells in all three states: static, dynamic, or alternating between static and dynamic states in the same cell culture container or containers, with the even distribution of cells in cell static culture following a dynamic culture. In the invented bioreactor system, the combined application of the magnetically controlled agitation and the cell culture container inversion as well as the combined application of the vertical rotating culture and horizontal static culture are the two strategies in building ideal bioreactors for the cell culture alternating between static and dynamic states in the same cell culture container, which can minimize the sheer-stress and provide cells an ideal metabolic environment.
priorityDate 2013-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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