http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9351932-B2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9c0917c34b99b09b05f55e8479f912ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aee48b2c67e5f6b7e8854561615d4276 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S514-812 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-906 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-773 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-907 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1271 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1277 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 |
filingDate | 2014-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d12d81b440da20b6b9207aa3e871d927 |
publicationDate | 2016-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-9351932-B2 |
titleOfInvention | Method and system for synthesizing nanocarrier based long acting drug delivery system for methadone |
abstract | The embodiments herein provide a nano-carrier system for delivering a long-acting injectable drug of methadone and a method of synthesizing the same. The methadone entrapped nanoparticles are prepared using a lipid/phospholipid core which is coated by a polymer. The lipid and phospholipid are dissolved in organic solvent. This solution is transferred into an aqueous phase consisting of distilled water or a buffer. A solution of polymer is added drop wise. The drug entrapped nanoparticle formation is achieved by diffusion of the organic solvent within the aqueous solvent to obtain the nanoparticles. The drug gets entrapped within the nanoparticles via the anti-solvency effect of the aqueous matrix. The resulting drug nanocarriers are capable of releasing the drug in a slow rate upon injection. The synthesized drug carrying nanoparticles are cryopreserved stored for future administration. For better storage, the nanodispersion is dried to form a powder. |
priorityDate | 2014-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.