http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9340543-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_436c80ac97c18c9be85d896bfe12b8b5 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D455-03 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D455-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-22 |
| filingDate | 2014-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ce02a589561b47aac4330347dd50b8f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b87997cc63ff0049094117a8a47f0071 |
| publicationDate | 2016-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-9340543-B2 |
| titleOfInvention | Helquat derivatives, preparation thereof, and use thereof as medicaments |
| abstract | The invention provides helquat derivatives of general formula I, wherein substituents R 1 and R 2 are independently selected from a group comprising H and C 1 to C 3 alkyl; up to three of S 1,2 , S 1′,2′ , S 3,4 and S 3′, 4′ are present, each of S 1,2 , S 1′,2′ , S 3,4 and S 3′,4′ independently represents a linker consisting of a bivalent hydrocarbon chain having 3-6 carbon atoms; one or two atoms selected from the carbon atoms with the descriptor 2, 4, 2′, and 4′ are substituted with a substituent R 3 of general formula II or general formula III wherein R 4 is substituted or unsubstituted aryl; T 1 and T 2 independently represent a bivalent hydrocarbon chain having 2-5 carbon atoms; and anions (X 1 ) − and (X 2 ) − independently represent anions of pharmaceutically acceptable salts. n The helquat derivatives are useful as medicaments in the treatment of diseases related to increased cellular proliferation, such as oncologic diseases. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9932339-B2 |
| priorityDate | 2013-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 591.