http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9334273-B1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_751562df05f1831baef905641425c407 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-1892 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-34 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18 |
filingDate | 2015-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e04825b0e2ddab2ddedb88f45d601a9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c707fd863b0f2a03528d2b452b363227 |
publicationDate | 2016-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-9334273-B1 |
titleOfInvention | Efficient and stereoselective synthesis of 2′-fluoro-6′-methylene-carbocyclic adenosine (FMCA) |
abstract | The invention provides a new convergent approach for the synthesis of 2′-fluoro-6′-methylene-carbocyclic adenosine (FMCA) from a readily available starting material (Vince lactam) in fourteen steps. An efficient and practical methodology for stereospecific preparation of a versatile carbocyclic key intermediate, D -2′-fluoro-6′-methylene cyclopentanol by diazotization, elimination, stereoselective epoxidation, fluorination and oxidative reduction of the Vince lactam in twelve steps is also provided. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105969836-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105969836-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11082386-B2 |
priorityDate | 2014-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 308.