| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bdd054ce16298ed6e692bc83ded66835
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ca9a355da06a660ca1b663a80eb1efb3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c293b3e942cf4a21a47bce2026891a8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12ad56d39c088fe68b1631175d0c21f8 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6432
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6429
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-647 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 |
| filingDate |
2011-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2016-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_973437beb3f5eef097e94498c19867dd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a1fe4388437f06a0b03bd40ec40ecbc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7db873498e0bde6b81d5d5d7d199fbc8 |
| publicationDate |
2016-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9329192-B2 |
| titleOfInvention |
Polymer-coupled peptidases |
| abstract |
The present invention is directed to a simple process for the modification of the specificity of a peptidase of the hemostatic system by coupling polymers to the peptidase causing it to lose its reactivity in the hemostatic system, but enabling it to continue to react with certain inhibitors, effectors and substrates. The invention is furthermore directed to processes for the detection or quantitative determination of inhibitors of the peptidase in bodily fluids or other samples as well as to processes for their neutralization and/or removal from liquids. Finally, the invention allows the use of a polymer-coupled peptidase as drug and furthermore provides a device which makes use of such a peptidase in the removal of peptidase inhibitors from samples or from the bloodstream of a patient. |
| priorityDate |
2009-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |