| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8cebc6945801a40ae6fa973283b51d66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_83c0f316f901284a8aa99dd82f42413a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5e361e61adf19d613968bb3f1d41cd26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f08963258fab945c763e111d89c164e2 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-19 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-205
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-245
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R1-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-18 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-245 |
| filingDate |
2011-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2016-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec23f7c1b988d1d2fc1ba7f191a3aae5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1cc884f23513975737c3523ed13ecdf1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49200dc7a953e682ca1d734d7b3fda76 |
| publicationDate |
2016-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9309575-B2 |
| titleOfInvention |
Mutant strains of Escherichia coli, a method of testing potential antibacterial agents using said strains as well as a testing kit |
| abstract |
The subject of the present invention are mutant strains of Escherichia coli MG6165 (ATCC nr 47076) lacking all potassium transporters: Kdp, Kup and Trk (ΔKtrans), encompassing strains lacking at least one of the genes encoding mechanically gated channels mscS and mscL (ΔKtrans ΔmscS i/lub ΔmscL). In particular, it concerns Escherichia coli MG61655 (ATCC No. 47076) lacking all potassium transporters: Kdp, Kup and Trk (ΔKtrans), which additionally are devoid of the mechanically gated channel gene mscS— E. coli (ΔKtrans ΔmscS), the mechanically gated channel gene mscL— E. coli (ΔKtrans ΔmscL) and/or both the mechanically gated channel genes mscS and mscL— E. coli (ΔKtrans ΔmscS ΔmscL). The subject of the present invention is also a method of testing chemical compounds for potential antibacterial properties, making use of the abovementioned strains. Another subject of the present invention is a kit for testing chemical compounds as potential antibacterial substances, containing the abovementioned strains. |
| priorityDate |
2010-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |