| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_368cb43bbb7c0e027e2bebc87ba2fa2c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_73c958e1b3e8706804476bf94c92146b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_adf225ca4a6bf6190b6a2763410d1ebf |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2440-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2440-12 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C319-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-533
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-1077
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-05 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-533
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C319-18 |
| filingDate |
2012-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2016-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8245525b7251ba7d8e34bc659aaeb021
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4bd8a426495f0163222def2a0036a79 |
| publicationDate |
2016-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9309278-B2 |
| titleOfInvention |
Method for modification of organic molecules |
| abstract |
The present invention is directed to a method of alkylating a thiol group (R—S—H) or seleno group (R—Se—H) in a target molecule wherein the method comprises: reacting a target molecule comprising at least one thiol group with a compound of formula (I) or (II): n nwherein R is an acetyl group or any other acyl group or is a group comprising any one of:n n nor wherein R in formula (II) can also be an alkyl group; and wherein R′ is selected from a group consisting of a hydrogen, a methyl group and an ethyl group. In certain cases, the described methods may be used to install acetylated lysine analogs in target molecules (e.g., peptides, proteins). |
| priorityDate |
2011-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |