| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e0c5ce02d0433493b637206dfdb6501c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6dfc224d71233bcac668251a68f45663 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
| filingDate |
2014-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2016-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_585e9830f1bc231945fe80963af51f23 |
| publicationDate |
2016-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9297024-B2 |
| titleOfInvention |
Recombinant protein expression using a hybrid CHEF1 promoter |
| abstract |
The invention provides expression vectors and host cells for high-level expression of recombinant proteins. The expression vectors comprise Chinese hamster ovary elongation factor 1-α (CHEF1) transcriptional regulatory DNA elements and a cytomegalovirus (CMV) promoter and/or a human adenovirus tripartite leader (AdTPL) sequence. The invention achieves increased protein expression and better productivity of host cells compared to previously described expression systems. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021062217-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019139940-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9957525-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2016177335-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019071691-A1 |
| priorityDate |
2013-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |