Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8dbfd941a1bf1d628962233af2a374be http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dc6b7017ffc1561a2985fe8c6467abd4 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-412 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-20 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-38 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-16 |
filingDate |
2008-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2016-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b04ce314f969e4e07d6de17aaf0c9a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d59ab97cf7c3cb687f78dd74eeffd0b0 |
publicationDate |
2016-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9289533-B2 |
titleOfInvention |
Collagen scaffold modified by covalent grafting of adhesion molecules, associated methods and use thereof for cardiovascular and thoracic cell therapy and contractile tissue engineering |
abstract |
Materials and methods for improving the biological properties and electromechanical performance of collagen scaffolds used for cell transplantation, including the fixation of biocompatible reagents and adhesion molecules which control cell adhesion, apoptosis, survival and/or differentiation simultaneously. The grafting of adhesion molecules to collagen matrices renders same suitable for use in vascular and cardiothoracic surgery/medicine, as well as in cell therapy for the heart and in artificial heart muscle engineering. Also, a simple method for grafting and optimising the presentation of adhesion peptides or biological agents when the scaffold is made from collagen and/or contains accessible thiol, amine or carboxyl groups. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11744922-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11058749-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022155261-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019018942-A1 |
priorityDate |
2007-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |