abstract |
The invention relates to a new class of compounds able to inhibit with high affinity and selectivity the 5-HT7 receptor and having the following formula IV: n n n n n n n n n n wherein W is O; n K, L, M and Q is CH or nitrogen; n R 1 is hydrogen; n R 2 is hydrogen; and n Ar is an aromatic ring with the following formula: n n n n n n n n n n n n wherein X, Y and Z is CH; and R 3 is a five- or six-membered ring selected from the group consisting of: |