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filingDate 2008-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3681bfc29cbd19fee9f22664982c97d
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publicationDate 2016-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-9254266-B2
titleOfInvention Inhibiting surface enhanced crystallization of amorphous pharmaceuticals with ultrathin coatings
abstract The present invention provides surface-stabilized amorphous pharmaceuticals comprising an amorphous pharmaceutical substrate coated with a biocompatible immobilizing material. Amorphous pharmaceutical substrates that are prone to surface enhanced crystallization benefit from the present coatings. The coated amorphous pharmaceuticals of the present invention maintain their amorphous state and, therefore, their solubility over extended periods of time, relative to uncoated pharmaceuticals.
priorityDate 2007-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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