Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c72d118f5664072de841f9c5c34b9d99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_18bd559ca61252d5d9c48f6973f13bca http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_601c8dbf57bb5156041c6b2d21010bcc http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f7a0deb8290b5102c4d97f772d58cd47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ede007538ac694cd0190bfc93afd5fe http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d8800130c6010bf356821d4fc7a3b32 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y30-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-186 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1842 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H01F1-0054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-186 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1842 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y30-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y40-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01F1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-18 |
filingDate |
2012-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2016-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78a79cc9e9a2e0d7c7ff05356bc942c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27eac97fa5857383ca3a2e5b8baa31bb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a43203197c9fd1bbcd4ce4edbdd38ec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c39daf92c3ca6f6041dd1c7a849ecf6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3258c3a9f66a48521f0f2bbfbc10feba |
publicationDate |
2016-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9251937-B2 |
titleOfInvention |
Heat stable nanoparticle preparations and associated methods thereof |
abstract |
A method of sterilizing a nanoparticle preparation at a high temperature is provided. A plurality of nanoparticles are purified to form the preparation, wherein the nanoparticles comprise at least a core and a shell and the shell comprises one or more ligand species attached to the core. The nanoparticle preparation is made by a purified nanoparticle composition, a carrier fluid and an excess of the one or more ligand species not attached to the core. The ligand species attached to the core and the excess ligand species added after purification are structurally identical. The nanoparticle preparation provided by the present invention may be used as contrast agents in medical imaging techniques such as X-ray and magnetic resonance imaging. |
priorityDate |
2012-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |