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filingDate 2014-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e181def852f0e162b4e9b90b240200e3
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publicationDate 2016-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-9243248-B2
titleOfInvention Oligonucleotides for RNA interference and biological applications thereof
abstract The invention relates to compositions comprising double-stranded oligonucleotides of identical or different sequences and/or length, said oligonucleotides having sequences 3′ N 1 N 2 . . . N i-1 N i . . . N j 5′ wherein— 3′ N i . . . N j 5′ is half of a double-stranded 19-28 mer oligonucleotide of sequence complementary to a target nucleic acid sequence present in a living cell, and— 3′ N 1 . . . N i-1 5′ is a 3-50 mer overhang of sequence allowing oligomerization of said double-stranded oligonucleotide. Compositions of transfection comprising said oligonucleotide compositions and there used for therapeutical application.
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