Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24a2813be67d5e8111c74891dcc38ee6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_345c329479c46b1f183ee80edc721a1b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9ebe6237abaf10148e22453471c038ce http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_55d9c177fb2d262c10d4058281c5a88b |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-22 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-22 |
filingDate |
2007-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2016-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b894b243f8884f8a00ca817cd538f4fc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_165c4fb1722714d40652d5d53248925e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d35e12b71c1bf97ed8f4113b2b5335b6 |
publicationDate |
2016-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9228167-B2 |
titleOfInvention |
Method for controlling the growth of cell culture |
abstract |
In a method for controlling the growth of microbes grown in a medium to high cell-densities by the fed-batch technology, a two-phase system, having a liquid phase (cultivation medium) and a solid or gel phase, the solid or gel phase provides a source of substrate-delivering polymer which is turned by an enzyme in a controlled way into a growth-limiting substrate or pH adjusting agent. Also described is a method for restricting the synthesis of growth-limiting metabolites and preventing oxygen-depletion in microbial cell cultures. |
priorityDate |
2006-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |