| abstract |
The present invention relates to compounds of formula I: n n n n n n n n n n n n in which n, R 1 , R 2 , R 3a , R 4 and R 5 are defined in the Summary of the Invention; capable of inhibiting the activity of MEK. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of hyperproliferative diseases like cancer. |