| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07c9542186133097bd6bbb7d92393090 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2602-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2102-24 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C35-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C401-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C401-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C35-32 |
| filingDate |
2013-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2015-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c281f415e8eca6ccd916d8a7744d004
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e32c7cd7ab95eb4f3df6f918a37ecd0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ecde363463fef2cc95393496a27165a3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_214f00a70b0c27e7ccb07906cd20d5f2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70ac0a37ab754ca4f17e77681d361e39
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46c5c6a1b66f4232e0de85dbf1dff1a9 |
| publicationDate |
2015-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9212137-B2 |
| titleOfInvention |
Crystallization of (20R,22R)-2-methylene-19-nor-22-methyl-1α,25-dihydroxyvitamin D3 and related precursors |
| abstract |
Disclosed are methods of purifying the compound (20R,22R)-2-methylene-19-nor-22-methyl-1α,25-dihydroxyvitamin D 3 to obtain the compound in crystalline form. The methods typically include the steps of dissolving a product containing the compound in a solvent comprising hexane and 2-propanol, cooling the solvent and dissolved product below ambient temperature for a sufficient amount of time to form a precipitate of crystals, and recovering the crystals. Certain diol precursors formed during the synthesis of the compound and its diasteromers also may be obtained in crystalline form using ethyl acetate as a solvent. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11697635-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019079279-A1 |
| priorityDate |
2012-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |