Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_56274197ad47993b10261ead432100d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43ca404e52f85966335e7a6abcac78af http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_014fc85627d940c9967acab943f2d2f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d85916a94a083ee31c684e7e4e361426 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_62528665b129ce4e198964f00919e2a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d339290b12515f2a2054d9c4019172c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bd8eebc365ac55c495b8513e73f259bc http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c74106d12ef602c2355bffd193d0d83f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_460b7c7464d382e69e2fa3840c1f4a86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_663236c6dd32478f15eaa2c44db8aed8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8ba5557262d9bf8846bbaa2fe725462c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1ce905b09b4c326027e10b6ac07d68cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_072f84af87c72256eb6656a49664f2a0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ee33b0e3e7398cf6fc957eeee59d510 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2535-131 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2527-107 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6881 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6832 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2007-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2015-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93b051245a80cd307a0fe1efa78dc773 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33a46df35433d831f7646e23930d02ee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4debcc006547c1015d92eec4fc5bd5b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10310c090a819935702185c03ebae372 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_290e04c43478a91f397ceda9eb68bcee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88d23c1977103f322ef1696188045765 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_553d5e1706f4350d7bb73cecf80b5ccd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ebe322b4412fe6b31b2f1c7a274c0c85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9170f4372e3bc9a6745aed77288baa52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0afa77aa7ae986f37be61905cdfd1e8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68afbdb45b351994d1cb2a5af61fc8f7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bbe3729982852f321b1b5461f24c28f7 |
publicationDate |
2015-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9200323-B2 |
titleOfInvention |
Hybridization methods using natural base mismatches |
abstract |
The present invention provides an improved nucleic acid hybridization process employing a modified oligonucleotide probe comprising naturally occurring nucleotide bases. At least one nucleotide in the modified oligonucleotide is artificially mismatched relative to the control nucleic acid in addition to any mismatches arising from a variant nucleic acid target containing a sequence variation. The artificial mismatch and the sequence variation positions are separated from one another on the oligonucleotide by six to nine nucleotide positions. |
priorityDate |
2006-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |