| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b113979c0f9dc5df62be0eefede4c59e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8a997f191569b010e0784b572cd57701
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_32780ac72b4de8d1a8ca1465b5336a2b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1a37ae9b1a8d1b15f49cfcbfeca04349
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_813067e4d746c5f6cedb5d3d91e1c9dc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f0933641bf64072d12216ad03ec6c32e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70514
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70517
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-7051
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70596
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4703
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-912 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5041
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5047
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57426 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate |
2012-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2015-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff3786e567c84c1b343d78bd6562ac7a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_659e648d243a66ab8fe8f9fe5bd1abab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e84d67da341b1ffd0b430a173bb30881
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86dc762d8df603ffbe4efaba40b3cd50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20ebd02f6ad480d630349633e5b9e501 |
| publicationDate |
2015-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9182385-B2 |
| titleOfInvention |
Methods for diagnosis, prognosis and methods of treatment |
| abstract |
This invention is directed to methods and compositions for diagnosis, prognosis and for determining methods of treatment. The physiological status of cells present in a sample (e.g. clinical sample) can be used in diagnosis or prognosis of a condition (e.g. Chronic Lymphocytic Leukemia), in patient selection for therapy, to monitor treatment and to modify or optimize therapeutic regimens. The physiological status of a cell can be determined by comparing the intracellular status of one or more activation elements (e.g. the phosphorylation status of a signaling molecule) in a cell (e.g. a cancer cell) to that of another cell (e.g. a normal cell). The physiological status of a cell can be further classified by adding one or more modulators (e.g. an inhibitor or activator) to the cell in question. In some embodiments, the invention is directed to methods of determining a phenotypic profile of a population of cells. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9500655-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019147678-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11555073-B2 |
| priorityDate |
2007-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |