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publicationDate 2015-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-9169294-B2
titleOfInvention Anti-angiogenic molecules, nanostructures and uses thereof
abstract The disclosure is generally directed toward the design and synthesis of peptide amphiphile (PA) molecules that comprises a peptide configured to inhibit angiogenesis. The peptide amphiphile comprises a hydrophobic tail, peptide sequence capable of beta-sheet formation; and a peptide, wherein the peptide is configured to inhibit angiogenesis. Optionally the PA further comprises a flexible linker between the peptide sequence capable of beta-sheet formation and the peptides. Further this disclosure is directed to nanostructures comprising peptide amphiphiles configured to inhibit angiogenesis.
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