| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6a2cc904b7a14e425d8108729f1d0fa5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_14baf029c9dbc6301e9d2a9471d7acae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b34d3c266e911f861948ab7910b4bc04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b62bc1c79be590de4dd195334b04d46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a23768dbf9d8ef98eeeaa67e8b3127a |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-438
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-438
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-107 |
| filingDate |
2010-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2015-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8ef8dc3449c151a8646669f5e68a1d7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e39267ec25feb0bcc76b5a473624438
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50aad6c4412fcfadbc2cbd6449f97c90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54b82d91dad7e87d4b629aa16c44f162 |
| publicationDate |
2015-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9168248-B2 |
| titleOfInvention |
Spiro compounds useful as inhibitors of stearoyl-coenzyme A delta-9 desaturase |
| abstract |
Heteroaromatic compounds of structural formula (I) are selective inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD1) relative to other known stearoyl-coenzyme A desaturases. The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease, such as atherosclerosis; obesity; diabetes; neurological disease; metabolic syndrome; insulin resistance; and liver steatosis. |
| priorityDate |
2009-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |