Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_056ae068f02098df93c0e3050ba18a06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6df71e6329398fab8710decf297ec505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61f88efcda59d7062a4252ecf6886f58 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2101-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-143333 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-08 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C311-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C303-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-003 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C303-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-24 |
filingDate |
2012-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2015-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cbd6da99f0929b941ff406f2f612772d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78ad26d03aa665658156bfa8eccdb65f |
publicationDate |
2015-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9156778-B2 |
titleOfInvention |
Cross-coupled peptide nucleic acids for detection of nucleic acids of pathogens |
abstract |
Disclosed is a method for lowering the detection limit in a method of detecting a nucleic acid comprising (i) contacting a solution comprising a first PNA with a substrate having a second PNA affixed thereto, the second PNA comprising at least one trans-cyclopentane residue, wherein the first PNA has two linker-attached biotins attached thereto and the first and second PNAs being complementary to different portions of a target DNA; (ii) contacting a sample suspected of containing the nucleic acid with the first and second PNAs; and (iii) determining the presence of the reporter molecule on the substrate. Also disclosed are a detection assay and a kit for detecting a target nucleic acid. |
priorityDate |
2006-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |