Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0de5b947a709b94417bf27d5cd972ad3 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-11001 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 |
filingDate |
2014-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2015-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_137fd23227edc006b2766499edebe139 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a983e52d379e91db0ab8cbf71ce936dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_176757d762a5366fe8e76a97f72c104f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f26c5c4e4a08c2cacbfc562302081c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_848da70f13d0639f23c82dc490c636e4 |
publicationDate |
2015-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9132174-B2 |
titleOfInvention |
Treatment of heart disease by inhibition of the action of ribosomal S6 kinase 3 (RSK3) |
abstract |
The present invention provides a method of protecting the heart from damage, by administering to a patient at risk of such damage, a pharmaceutically effective amount of a composition which inhibits the interaction of RSK3 and mAKAPĪ², or the expression or activity of one or both of those molecules. This composition may be in the form of a peptide that specifically inhibits mAKAPĪ² binding to RSK3 or in the form of an siRNA construct which inhibits the expression of RSK3. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2022143138-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11229679-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019010301-A1 |
priorityDate |
2013-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |