| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ffb6ed7c81a87bd3efa30da2d67ab693
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8d8d30805708f0d2affd52c695145421
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_132c9fb6214fa87a438f3b62ee9e17a5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c0e7dfce989565c19cd11d578c4cdf75 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-723
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70567
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B30-04 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-566 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B30-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566 |
| filingDate |
2007-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2015-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_144dd7ef2878bb4dd9d10162040da801
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c92956b6b93e2cc944d5d4035941c54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79fdebc5279b680c4f034aa3bcd2089b |
| publicationDate |
2015-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9128087-B2 |
| titleOfInvention |
Nuclear receptor assay |
| abstract |
The present invention relates to methods for measuring compound efficacy and potency on nuclear receptor-co-regulator interaction, comprising the steps of (a) co-incubating at least one nuclear receptor and at least one compound under conditions that allow interaction; (b) co-incubating the nuclear receptor-compound mixture of step (a) with an array of co-regulators, under conditions that allow compound modulated receptor-co-regulator interaction; (c) determination of compound-modulated receptor-co-regulator interaction in function B of co-regulator concentration, and (d) determination of compound-modulated receptor-co-regulator interaction in function of compound concentration; wherein steps (c) and (d) are performed in a single assay. |
| priorityDate |
2006-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |