http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9128081-B2

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publicationDate 2015-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-9128081-B2
titleOfInvention TDP-43-storing cell model
abstract Disclosed is a transformed cell (a cell model) which can form a cytoplasmic inclusion body derived from TAR DNA-binding protein of 43 kDa (TDP-43) that is found in the brain of a patient suffering from a neurodegenerative disease such as FTLD and ALS. The transformed cell is characterized by having, introduced therein, a promoter capable of functioning in a host cell and a mutant TDP-43 gene.
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