| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4b3d8314a382abec885221e0d6901ccc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3f094cb1a8cc8939264974f99a812291
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2174dd7ac8f6855b2b6a2019d2e222ad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c3f0be1f3555693631b84ee58f1788a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-414
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-227
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-495
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3604
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1841
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3608 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-495
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22 |
| filingDate |
2012-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2015-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0e0032cccd63eeffb7771f717ca5fb6 |
| publicationDate |
2015-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9084757-B2 |
| titleOfInvention |
Osteogenic device for inducing bone formation in clinical contexts |
| abstract |
This invention relates to an osteogenic device for the de novo induction of bone formation in a mammal. The device contains at least one transforming growth factor-β3 isoform and a retention matrix. The device is introduced by direct injection or surgical implantation into an area where de novo bone formation is desired and, once implanted, the retention matrix acts to retain the TGF-β3 isoform at its place of introduction and forms a scaffold for generated bone, the induction of which is promoted by the TGF-β3 isoform. The device may be used to induce bone growth where bone has been debrided in a surgical procedure and it may also be used to transform neoplastic primary and/or metastatic secondary masses into bone thus facilitating surgical debridement thereof. |
| priorityDate |
2005-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |