http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9062049-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4df528a427f4bc7e35e5ccd29156f460 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3b17c63869c4fdc741cd2c9aa2601b0b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5053f82a7cd17c60822674b657cfb89e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fc3df1c6b4084c4b8266c74f992438b9 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 2012-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_158b2103fa7ea2f192c558adff95c2a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff59e5b9f3243b7105d23c0733c329dd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60d9b73606cc95e087f0c0b7ba68c02a |
| publicationDate | 2015-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-9062049-B2 |
| titleOfInvention | Process for the preparation of paliperidone |
| abstract | The present invention provides a process for the preparation of paliperidone or a pharmaceutically acceptable salt thereof, wherein the process comprises condensing a compound of formula (II) n nwith a compound of formula (III) or a salt thereof,n n nin a suitable solvent and a base, in the presence of a catalyst and an inhibiting agent, wherein the inhibiting agent is added to the reaction system before the compound of formula (II) and compound of formula (III) have reacted or as the reaction of the compound of formula (II) and compound of formula (III) is initiated, and optionally converting the paliperidone to a salt thereof, wherein X is a suitable leaving group. The present invention also provides substantially pure paliperidone or a salt thereof, paliperidone or a salt thereof as prepared by the process and uses of the paliperidone or salt thereof. |
| priorityDate | 2011-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 87.