Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b8e361ec55430ad8ea57f397ebe59434 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d6f7da1e425c8a3ef1da21e08f4c196 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f95c33ea8299e31347ef992ee0b0609 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_077bdaa01cc91db63b5639d3fd23ba67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7acc94043361a97eb686917eb8140950 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0636 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2563-137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2531-137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-0424 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-0415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0887 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2565-632 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0829 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0654 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0809 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01F13-0076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502761 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-50273 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6862 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-658 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01F33-3031 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01F13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L3-00 |
filingDate |
2009-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2015-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0fd82ff5b72e11316f6d51d38fd4e7c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_830934f5cb914628314be77c60148e6a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e8c097d7e2c3467274730cb3f605948 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91e837e5c50b33815ac904258d766d8b |
publicationDate |
2015-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9057099-B2 |
titleOfInvention |
Enhanced on-chip SERS based biomolecular detection using electrokinetically active microwells |
abstract |
A method for detecting target nucleic acids such as SNPs is provided. The method comprises performing a ligase detection reaction (LDR), performing surface enhanced Raman scattering (SERS) on the LDR, and analyzing the outcome of the LDR using analysis and/or quantification of the SERS by detecting an emitted Raman signature. The LDR-SERS method can be used for sensitive and specific detection of any nucleic acid sequence of interest. A microfluidic SERS detection device is also provided. The device comprises electrokinetically active microwells for mixing and concentrating analytes and in which analytes can be quantified. The device can be used for performing the LDR-SERS method in optofluidic chip format. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110412097-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110412097-A |
priorityDate |
2008-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |