| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ed851666433ba6ee492351fbcac22a3f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c9cf31c21b1ce77fc5fcf384e250b2bd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a2f2c5972365172d35633c3e715a4137
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_385f5aa2aafa5c58aaf360229ab1308f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_601323fda973cb72b92bb771623446cd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01f32c33ef74d97ca314f3d35acf6fd8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-535
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-353
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-075 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-535
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-075 |
| filingDate |
2010-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2015-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ba51e59e81fee21d711d969abcb55cc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77f2da984f493849536def06822fa3c7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4eea9825b51ed739df2be9a5ad8c260f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85af6602a3f09022743b19af3c3d7ed2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2102af0835ebf64efac979e54edd311c |
| publicationDate |
2015-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9040673-B2 |
| titleOfInvention |
Synthesis and identification of novel RSK-specific inhibitors |
| abstract |
A composition comprising an SL0101 [kaempferol 3-O-(3″,4″-di-O-acetyl-α-L-rhamnopyranoside)] derivative compound that has enhanced ability to inhibit RSK activity, relative to the parent compound is provided. The compounds have utility for treating any disease or conditions characterized or associated with excess or undesirable RSK activity. For example the RSK inhibitors of the present invention can be used to reduce the proliferation of neoplastic cells or for inhibiting the establishment or maintenance of an intracellular pathogenic infection by pathogens whose pathogenicity derives in part from the pathogen's ability to impede endosomal/phagosomal maturation in the host cell. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018013761-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10980808-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109715158-A |
| priorityDate |
2009-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |