| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1721d75f5bf603447ec5a26b5c1c0be0 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2300-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-465 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-47 |
| filingDate |
2013-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2015-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8a46a782ac2d30c6f0d2f63731d1b73
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e0eb7a6bd7b3a6454ef2a155ffa561c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36609b95eba3275e6d3f8d5e2fe9e652 |
| publicationDate |
2015-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9040040-B2 |
| titleOfInvention |
Enzyme combinations to reduce brain tissue swelling |
| abstract |
Tissue fixed charge density (FCD) is identified as another potential therapeutic target for reducing brain tissue swelling. Reduction of the FCD could reduce the thermodynamic force driving water entry into the brain. The present invention discloses chondroitinase ABC (ChABC) reduces tissue FCD and reduces tissue swelling, indicating that it may be an effective treatment to reduce edema and control intracranial pressure. |
| priorityDate |
2010-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |