http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9029133-B2

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filingDate 2004-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df9894e5d3a4f699ee7142ff2801fb42
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publicationDate 2015-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-9029133-B2
titleOfInvention Recombinant virus comprising an intact tumor-therapeutic antibody with human constant regions and the use thereof
abstract The present invention provides a recombinant virus containing a nucleotide sequence encoding a tumor-therapeutic full-length antibody with human constant regions, and uses thereof. After a nucleotide sequence of a gene encoding a tumor-therapeutic full-length antibody with human constant regions of the light chain and the heavy chain is inserted into the genome of a recombinant virus, the tumor-therapeutic full-length antibody with human constant regions can be efficiently expressed in tumor cells, thereby inhibit the growth and metastasis of tumors.
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