| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_55aa6c871e2f49f2b549baa9abe9b887
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_606af2ecb5dfa3cdf08556ddac6f9657
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8598c1633f77124adc5ef4432ea2a5a6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a694a918c8e6e9185265020c89a37203
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b2378590caedd1d21ba51021d36d2a89
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba10f882a347602cac65ced0d60d6fed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d600599a7e5da5fc008809e890014fc7 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0017
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B5-0071 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 |
| filingDate |
2012-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2015-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de1555ec09ea017f3b116a67da8a52f1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1732f4e0d4baf720331e4049b0d98f56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04b53f891240556b541598e75ef5e120
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e65ad5ba7c232b8cc8eb652a2e7f689
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22d85c4bdf0721e46a943d49cc50e724
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce9c2f30ccbe0d5a372c331025c81d3f |
| publicationDate |
2015-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9017646-B2 |
| titleOfInvention |
Process of evaluating blood-brain barrier permeability of stroke rat by using fluorescent substance |
| abstract |
A process of evaluating blood-brain barrier permeability of a stroke rat by using fluorescent substance is disclosed. This process uses an Evans blue dye having spontaneous fluorescence properties, in combination with the use of a new non-invasive in vivo imaging system (IVIS), to obtain fluorescent signals so as to assess the change in the blood-brain barrier permeability of rodents after a cerebral artery stroke model surgery. In operation, an Evans blue dye is injected into a stroke rat of middle cerebral artery occlusion model. A non-invasive in vivo imaging system is used to detect the fluorescence distribution of the whole brain, and obtain images combined by the fluorescence images and optical images for the whole brain tissue. Thereby, the change in the blood-brain barrier permeability of the stroke rat can be completely realized. |
| priorityDate |
2012-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |