Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76ce918e62219aafa6ba3342d5a8664d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d394e3a458d9c31ac77246f6aec69865 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_75c1f2286d8b95413f5258705fb3deb3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9782f345aeacefcfb39c08e3b7e6b001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b763e5da3f6edf3d17f200c8b3c4f5eb |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-521 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54333 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54346 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-544 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-558 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-549 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-52 |
filingDate |
2009-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2015-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b7c23b4b12052f843becdd48e8c069d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9234345043cc7e9d0c705a0dfeed595 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4718de7ca0654a2899b3983f97d5929f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07716fc7d8e04349855baa60f5736a17 |
publicationDate |
2015-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9012240-B2 |
titleOfInvention |
Hydrogel nanoparticle based immunoassay |
abstract |
An immunoassay device incorporating porous polymeric capture nanoparticles within either the sample collection vessel or pre-impregnated into a porous substratum within fluid flow path of the analytical device is presented. This incorporation of capture particles within the immunoassay device improves sensitivity while removing the requirement for pre-processing of samples prior to loading the immunoassay device. A preferred embodiment is coreshell bait containing capture nanoparticles which perform three functions in one step, in solution: a) molecular size sieving, b) target analyte sequestration and concentration, and c) protection from degradation. The polymeric matrix of the capture particles may be made of co-polymeric materials having a structural monomer and an affinity monomer, the affinity monomer having properties that attract the analyte to the capture particle. This device is useful for point of care diagnostic assays for biomedical applications and as field deployable assays for environmental, pathogen and chemical or biological threat identification. |
priorityDate |
2008-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |