Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8286e2790c0bc4cdd7e6c6e64075fca5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9ce6a1b9c4f5f041a7cc5d509111188a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5f9919f83c35c74149e7eae8e63afee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8f0d61d62d86c276f17f51948cdebc45 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2525-186 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2525-119 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6855 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1093 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2007-02-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2015-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2dc216046fbfc971b6011c9e7574fac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd671de47ce976fd02a0e90b12f0a107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6f2644088eee9c8485843827cb5a4dd |
publicationDate |
2015-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-9012184-B2 |
titleOfInvention |
End modification to prevent over-representation of fragments |
abstract |
The invention relates to a method of preparing a 5′ and 3′ modified library of template polynucleotides and also the use of the 5′ and 3′ modified library of templates in methods of solid-phase nucleic acid amplification. In particular, the invention relates to a method of preparing a 5′ and 3′ modified library of template polynucleotides which have common sequences at their 5′ ends and at their 3′ ends, wherein over-representation of “end” sequences of the primary polynucleotide molecules from when the 5′ and 3′ modified library is generated is greatly reduced or prevented. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015197789-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10006081-B2 |
priorityDate |
2006-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |