| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e70c0aeade92d7571d955d3b90ea06e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01289 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0036
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-815
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-6427
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-6432
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-6458
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-6472 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-64 |
| filingDate |
2013-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2015-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_007e96a3b4a30231e6482bc4ee0aaa43
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cecea01f73ce0270eb7ca983449e9c8f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_818420efd7b5ccd9f7336fc0fcb45513
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c46fdd8d8fa0d1dbab01fae03c783b1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5346631152dadce7211fd01ce3228546
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bc4be666277b305a081f416a1201775 |
| publicationDate |
2015-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-9005940-B2 |
| titleOfInvention |
Down-regulation of a polynucleotide encoding a Sou2 sorbitol utilization protein to modify lipid production in microbial cells |
| abstract |
Recombinant microbial cells are disclosed herein that comprise (i) a down-regulation of an endogenous polynucleotide sequence encoding Sou2 sorbitol utilization protein, and (ii) a polyunsaturated fatty acid (PUFA) biosynthetic pathway. The down-regulation of the polynucleotide sequence encoding Sou2 sorbitol utilization protein can increase the lipid content of the microbial cells and/or decrease the total amount of sugar alcohols produced by the microbial cells. Also disclosed are methods of using the recombinant microbial cells to produce oil containing omega-3 polyunsaturated fatty acids such as EPA. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014186906-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9701989-B2 |
| priorityDate |
2012-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |