| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_94a748fc084a0b56cd409f83981fb5bb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ce5bb20464b085adead0b950492b6aba
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_123a6e25d327689f50c09c1d6082d525
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_94c8ad6c3080d00179e8b926c10e6b4d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_441e08791d5972d8188805ce31749300 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-23
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-60 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-93
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B50-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B20-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B30-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate |
2003-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2015-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cceea4472bc6854d831d98c99c4bd24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e71f006649d12c08815c271f1b87ddf9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3b55cf1c30ea14488938b6153f3420f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e399b38bec65dd909856c32311fa93df |
| publicationDate |
2015-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8999897-B2 |
| titleOfInvention |
Protein tag comprising a biotinylation domain and method for increasing solubility and determining folding state |
| abstract |
The use of a tag moiety comprising a biotinylation domain, such as biotin carboxyl carrier protein (BCCP), as a protein folding marker and protein solubility enhancer in the orientated surface capture of products of heterologously expressed genes is described. Methods for increasing the solubility of proteins and determining the folded state of a protein are also disclosed. The uses and methods of the invention can be carried out in a multiplexed manner on more than one protein in the formation of libraries. In addition the nucleic acid molecule encoding the biotinylation domain of the tag moiety can be used to increase the proportion of clones in a library that express the protein of interest. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020252405-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020252404-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020185632-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021046451-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9645146-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019241315-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020086742-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017180587-A2 |
| priorityDate |
2002-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |