| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f6df56a4e9b17d56d9c57dcf04c46b3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_25a7feab9d0f978eb59fc331e82e8db5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43821c1c39ab671e60e9d446da5949a5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7b1aa895df15621021a1d37bbafe0fd9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_52a58fe0c74c738269f0cd5ea75cfda0 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2531-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2521-301 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6806
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2008-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2015-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd6e519c51efcf967b7ca7bd320b4299
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4d36676bd7b4807628abef3ecda2a9e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61281084e9448b652d0c62678b3f2ee8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_28ca3c338bb8b05a77059feb4aa94bd7 |
| publicationDate |
2015-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8999634-B2 |
| titleOfInvention |
Nucleic acid detection combining amplification with fragmentation |
| abstract |
Provided herein are methods and compositions for detection of a nucleic acid target in a sample. The methods and compositions use primer directed amplification in conjunction with nucleic acid fragmentation. The methods have high sensitivity even in the presence of a large amount of non-target nucleic acid. Also provided are oligonucleotides and kits useful in the method. Exemplary nucleic acid targets are those with mutant gene sequence such as mutant sequence of the EGFR, APC, TMPRSS2, ERG and ETV1 genes. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11359248-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11345968-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11788153-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11643694-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11519039-B2 |
| priorityDate |
2007-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |