| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4820fd810c475a5615a6f391880048ce |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2602-10 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D303-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D303-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-60 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-66
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D303-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-02 |
| filingDate |
2014-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2015-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_136ebb118467ca9c0bc850a05b0a9169
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b3566d85da38f7f4a50a3f5bc8ad2a6 |
| publicationDate |
2015-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8987503-B2 |
| titleOfInvention |
Process for the synthesis of aminaphtone |
| abstract |
The present invention concerns a new process for the synthesis of aminaphtone, which makes use of non-toxic solvents and reagents, under mild reaction and temperature conditions. The aminaphtone obtained with the method of the present invention also has a purity of at least 98% in weight. The method comprises the following steps: a) epoxidating menadione 1 to provide epoxide 2, b) acidifying epoxide 2 to provide hydroxynaphthoquinone 3, c) esterifying between hydroxynaphthoquinone 3 and 4-aminobenzoyl chloride to obtain compound 4, and d) reducing compound 4 in the presence of a reducing agent in water to obtain aminaphtone. |
| priorityDate |
2013-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |