Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_709b4a26ef028713f9b302509eb824d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_90ad6161e653d43dfe1ab037c88ad786 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a20a7c4a7cc6fb18643ad7d7831bff9b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14133 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14132 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-768 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-864 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-768 |
filingDate |
2011-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2015-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5b88552d911d4ad84aee6209c68ac9e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a086bb452d29b3b2540a8c43078c016 |
publicationDate |
2015-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8980247-B2 |
titleOfInvention |
Parvovirus methods and compositions for killing neoplastic cells |
abstract |
According to the invention, parvoviruses such as the adeno-associated virus Type 2 (AAV2) are found to be oncolytic, selectively mediating apoptosis in cancer cells and their precursors, while leaving healthy cells intact. The invention also includes a method of killing cancer and other neoplastic and preneoplastic cells by administrating to said cells the AAV2 proteins Rep78 or Rep 68, expression constucts encoding the same, or pharmaceutical compositions comprising the same. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11013774-B2 |
priorityDate |
2004-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |