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filingDate 2011-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6f584cc9ebb07494cd5ebea0736f5de
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publicationDate 2015-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-8962241-B2
titleOfInvention Triggered molecular geometry based bioimaging probes
abstract The present embodiments relate to engineering imaging probes based on “triggered molecular geometry.” Upon detection of a molecular signal, nucleic acid hairpin monomers assemble an imageable molecular shape with prescribed geometry. In some embodiments the prescribed shape can be imaged directly. In some embodiments, the prescribed shape can serve as a spatial organizer or amplification scheme for other imaging entities, such as fluorophore and fluorescent proteins.
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