| abstract |
The application is directed to compounds of Formula I-A n nand pharmaceutically acceptable salts and solvates thereof, wherein Cy, R 1a -R 3a , R 4a , and R 4b are defined as set forth in the specification. The invention is also directed to use of compounds of Formula I-A to treat disorders responsive to the modulation of one or more opioid receptors, or as synthetic intermediates. Certain compounds of the present invention are especially useful for treating pain. |