Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a72a873b004b3fbaa1a97b4f669edd87 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2537-125 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2521-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2525-161 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2330-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2525-205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-10 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6823 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-682 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6818 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6811 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6834 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 |
filingDate |
2013-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2015-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1cc7fa2bfe10732cc112743084ddea3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f11d0b0b71672ec399f41188cc95380f |
publicationDate |
2015-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8945836-B2 |
titleOfInvention |
Multicomponent nucleic acid enzymes and methods for their use |
abstract |
The present invention relates to Multicomponent Nucleic Acid Enzymes (MNAzymes) and methods for their use. MNAzymes comprise two or more oligonucleotide components which self-assemble in the presence of one or more MNAzyme assembly facilitator molecules to form a catalytically active structure. Compositions for making MNAzymes, and collections of MNAzymes are provided. Also provided are methods for using MNAzymes for the detection, identification and/or quantification of one or more targets. The methods can be practiced in solution-based assays or in assays where one or more reaction components are attached to a support structure. The methods allow for multiplexing the MNAzyme detection to detect multiple targets in a single reaction. Also provided are kits for making the compositions, and for practicing the methods provided herein. |
priorityDate |
2005-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |