| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b5e1f250ff8c0ab4b6a8667b9a138f04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_56ed8782dda014cb990dd56e6c06b1ca
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4995f9f283818abded9ed15388db98cd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0aba279ae9ac78a9468a07e1e277b295 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-675
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-732
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-6436 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C11C3-10 |
| filingDate |
2012-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2015-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2df2bc679e70845103d02c57be7735dc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cab71e8ca27db0ab4fb5885d16b97b35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d734115423f1dd1e040e87d176ef141 |
| publicationDate |
2015-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8936922-B2 |
| titleOfInvention |
Synthesis of fatty alcohol esters of alpha-hydroxy carboxylic acids and their use as percutaneous absorption enhancers |
| abstract |
The present invention provides a novel approach for the preparation of fatty alcohol esters of α-hydroxy carboxylic acids. In one form of the invention, the target fatty alcohol ester of α-hydroxy carboxylic acid is produced by converting a lower alkyl ester of α-hydroxy carboxylic acid into a fatty alcohol ester of α-hydroxy carboxylic acid via alcoholysis (i.e., transesterification). The transesterification process is an equilibrium reaction, catalyzed chemically (i.e., with acids or bases) or enzymatically, that is shifted in the desired direction to produce the desired product. One way of shifting the reaction in the direction of the desired product is by reducing the concentration of one of the products (e.g., distillation of a lower-boiling alcohol as it is formed). Another preferred way of shifting the reaction in the direction of the desired product is by increasing the concentration of one of the reactants. |
| priorityDate |
2004-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |