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filingDate 2004-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0349ab4edff80db85b9c38beb7aa97f2
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publicationDate 2015-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-8932603-B2
titleOfInvention Modified antibody
abstract Recombinant antibody-based molecules that trigger both T-cell and B-cell immune responses are disclosed. The recombinant molecules are comprised by at least one targeting unit and at least one antigenic unit connected through a dimerization motif. Also disclosed are nucleic acid molecules encoding the recombinant antibody-based molecule and methods of treating multiple myeloma or lymphoma in a patient using the recombinant antibody-based molecules or the nucleic acid molecules.
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