Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1271 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1275 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7048 |
filingDate |
2012-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63b1fce2ace25a29418d39a134d63241 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb9c0e8c3b39552227bc92776afb8962 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_306d5682ae182771c16daae5fa76e95b |
publicationDate |
2014-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8895055-B2 |
titleOfInvention |
Telodendrimer nanodiscs without apolipoprotein |
abstract |
The present invention provides a nanodisc without a membrane scaffold protein. The nanodisc includes a telodendrimer and a lipid; the nanodisc does not include a membrane scaffold protein. The telodendrimer has the general formula PEG-L-D-(R) n , wherein D is a dendritic polymer; L is a bond or a linker linked to the focal point group of the dendritic polymer; each PEG is a poly(ethylene glycol) polymer; each R is and end group of the dendritic polymer, or and end group with a covalently bound hydrophobic group, hydrophilic group, amphiphilic compound, or drug; and subscript n is an integer from 2 to 20. Methods of making the nanodiscs are also provided. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11369688-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11300572-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9642916-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11279749-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11207422-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110117312-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110117312-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11053322-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11219692-B2 |
priorityDate |
2011-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |