| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6f79749e86afce9444a364ab60ca3584
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb21369f0340b632f0d9e1d0fcf416f0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f5325ab8d0bdd6dc098b2bfbdb29f696 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C269-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-14 |
| filingDate |
2011-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2014-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a05c6cf09dd7164711e0a094b9646da5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7702d3a4106570debd1202585169f62e |
| publicationDate |
2014-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8889863-B2 |
| titleOfInvention |
Stereoselective methods, catalysts and intermediates for the synthesis of (−)-Nutlin-3 and related compounds |
| abstract |
The present invention provides methods and intermediates are provided for the preparation of (−)-Nutlin-3. Methods and intermediates are also provided for the enantioselective addition of aryl nitromethanes to aldimines. Bis(amidine) catalysts for the use in these and other reactions are also provided. |
| priorityDate |
2010-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |