| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c72d118f5664072de841f9c5c34b9d99
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f7a0deb8290b5102c4d97f772d58cd47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_420d7e18c6cb149367a13f4251d19470
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d8800130c6010bf356821d4fc7a3b32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_601c8dbf57bb5156041c6b2d21010bcc |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1842
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1845
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y15-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-055
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-18 |
| filingDate |
2010-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2014-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8853f79c71391d1d1bbe6a3ab653009c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a66a2901bf566de820eb7708c28aaabf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c80ef49d706404047dd3db7e89d2e01e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3733e297f51bd85ee2470573fe9346b |
| publicationDate |
2014-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-8889103-B2 |
| titleOfInvention |
Diagnostic agent composition and associated methods thereof |
| abstract |
A diagnostic agent composition is provided which comprises a nanoparticle composition and a pharmaceutically acceptable carrier or excipient. The nanoparticle composition comprises a nanoparticulate metal oxide and a phosphorylated polyol, wherein the phosphorylated polyol comprises at least two phosphate groups and one or more hydrophilic groups selected from the group consisting of polyethylene ether moieties, polypropylene ether moieties, polybutylene ether moieties, and combinations of two or more of the foregoing hydrophilic moieties. The disclosure provides detailed guidance on methods of making and using such diagnostic agent compositions. The diagnostic agent compositions provided by the present invention are useful as contrast agents for medical diagnostic imaging techniques such as magnetic resonance (MR) imaging and X-ray imaging. The diagnostic agent composition may be administered to a subject via a variety of techniques, among them injection, inhalation, and ingestion. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11359058-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11707509-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10799564-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11033608-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017087897-A1 |
| priorityDate |
2010-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |