Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e3830f35387a1c32061dea3ee310851 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1138 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
filingDate |
2012-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2014-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d216a0300c8bb464a6f43b4109ae97aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f2f688b5fa0af5b445bc9136bfceaa4 |
publicationDate |
2014-10-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8859752-B2 |
titleOfInvention |
SIRNA-based therapy of Fibrodyplasia Ossificans Progressiva (FOP) |
abstract |
This invention is directed to mutated Activin A type I receptor proteins (ACVR1) and isolated nucleic acids encoding same. The invention also relates to compositions and methods for siRNA-based regulation of mutated ACVR1 expression in the treatment of Fibrodysplasia Ossificans Progressiva (FOP). |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10106852-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015203918-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105254764-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11674154-B2 |
priorityDate |
2006-04-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |