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filingDate 2010-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2014-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-8853271-B2
titleOfInvention Method for inhibiting activity and/or expression of matrix metalloproteinase, inhibiting phosphorylation of mitogen-activated protein kinase, and/or promoting expression of collagen using tormentic acid
abstract A method for inhibiting the activity of matrix metalloproteinase (MMP), inhibiting the expression of matrix metalloproteinase, inhibiting the phosphorylation of mitogen-activated protein kinase (MAPK), and/or promoting the expression of collagen in a mammal is provided. The method comprises administrating to the mammal an effective amount of an active component selected from a group consisting of a compound of formula (I), a pharmaceutically acceptable salt of the compound, a pharmaceutically acceptable ester of the compound, and combinations thereof:
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