http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8853250-B2

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filingDate 2008-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a8c2099817ca1631614111f4c78d26e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68ac0b3f09559072f0754548ae58d4a6
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publicationDate 2014-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-8853250-B2
titleOfInvention Sodium channel inhibitors
abstract Compounds, compositions and methods are provided which are useful in the treatment of diseases through the inhibition of sodium ion flux through voltage-gated sodium channels. More particularly, the invention provides substituted aryl sulfonamides, compositions comprising these compounds, as well as methods of using these compounds or compositions in the treatment of central or peripheral nervous system disorders, particularly pain and chronic pain by blocking sodium channels associated with the onset or recurrence of the indicated conditions. The compounds, compositions and methods of the present invention are of particular use for treating neuropathic or inflammatory pain by the inhibition of ion flux through a voltage-gated sodium channel.
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priorityDate 2007-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226414460
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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5311271
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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID21923343
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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6438358
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID11174599
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID127686565
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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID12049213
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http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226395484
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Total number of triples: 1629.